RORC anticorps
Aperçu rapide pour RORC anticorps (ABIN932197)
Antigène
Voir toutes RORC AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Réactivité croisée
- Humain
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Réactivité croisée (Details)
- Other species not studied.
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Purification
- Protein G affinity chromatography
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Immunogène
- RORC antibody was raised in mouse using recombinant Human Rar-Related Orphan Receptor C
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Isotype
- IgG2a
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Indications d'application
- Optimal conditions should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- Lot specific
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Buffer
- RORC antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Conseil sur la manipulation
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.
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- RORC (RAR-Related Orphan Receptor C (RORC))
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Autre désignation
- RORC
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Sujet
- The protein encoded by this gene is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known, however, studies of a similar gene in mice have shown that this gene may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2. Two transcript variants encoding different isoforms have been found for this gene. Synonyms: Monoclonal RORC antibody, Anti-RORC antibody, RAR-related orphan receptor C antibody, TOR antibody, RORG antibody, RZRG antibody, NR1F3 antibody, MGC129539 antibody.
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Pathways
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway
Antigène
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